The Coastal Plain League announced Friday, June 9, 2006 that 72 players, both former and players signed for the 2006 season, were drafted in the 2006 Major League Baseball First-Year Player Draft. A list that featured 12 players selected in the first 10 rounds was highlighted by Tyler Colvin of Clemson. Colvin, who played for the Florence RedWolves in 2004, went in the first round, 13th pick overall by the Chicago Cubs.
The 72 players drafted is the most CPL alumni total drafted since the league started back in 1997. In 2005, 67 CPL alums were selected in the draft, while 66 were taken in the 2004 draft.
All but two, Asheboro and Columbia, of the 15 CPL clubs had at least one alum drafted. The Fayetteville SwampDogs, Florence RedWolves, Peninsula Pilots, Petersburg Generals and Wilmington Sharks each had eight players drafted, which was the most by any team this year. The Wilson Tobs were next with seven players drafted, followed by Martinsville with six. Outer Banks and Thomasville each tallied five draftees, while Edenton and New Bern notched four each. Spartanburg featured three drafted alumni, and Gastonia rounded things out with two alums taken in the draft.
The complete list of CPL players drafted follows:
| Round | Overall | Player | College/University | MLB Team Drafted By | CPL Team(s) |
|---|---|---|---|---|---|
| 1 | 13 | Tyler Colvin | Clemson | Chicago (NL) | '04 Florence |
| 3 | 94 | Joe Smith | Wright State | New York (NL) | '05 Edenton |
| 5 | 137 | Jason Godin | Old Dominion | Kansas City | '04,'05 Spartanburg |
| 5 | 155 | Chris Hatcher | UNC-Wilmington | Florida | '04 Wilson / '05 Wilmington |
| 7 | 198 | Michael McKenry | Middle Tennessee State | Colorado | '05 Fayetteville |
| 7 | 210 | Jonathan Baksh | Florida Tech | Toronto | '06 Martinsville |
| 7 | 215 | Don Czyz | Kansas | Florida | '05 Fayetteville |
| 7 | 219 | David Qualben | Pace | Houston | '05 Wilson |
| 8 | 227 | Josh Cribb | Clemson | Kansas City | '02, '03 Florence |
| 8 | 237 | Chase Christianson | South Alabama | Arizona | '06 Martinsville |
| 9 | 263 | Bridger Hunt | Central Missouri State | Los Angeles (NL) | '06 Fayetteville |
| 9 | 277 | Andrew Cruse | South Carolina | Philadelphia | '05 New Bern |
| 11 | 319 | Heath Rollins | Winthrop | Tampa Bay | '04 Florence |
| 11 | 325 | Anthony Martinez | Louisburg JC | Baltimore | '05 Peninsula |
| 11 | 336 | Steve Singleton | San Diego | Minnesota | '04 Thomasville |
| 12 | 351 | Gavin Dickey | Florida | Florida | '04 Petersburg |
| 12 | 365 | Brad Stone | Quincy (Ill.) | Florida | '05 Edenton |
| 12 | 373 | Ryan Khoury | Utah | Boston | '04, '05 Edenton |
| 12 | 376 | David Carpenter | West Virginia | St. Louis | '06 Peninsula |
| 12 | 374 | Nick Peterson | Tampa | New York (AL) | '05 Martinsville |
| 13 | 381 | Joseph Kantakevich | William & Mary | Florida | '06 Outer Banks |
| 13 | 393 | Mike Epping | New Orleans | San Diego | '05 Petersburg |
| 14 | 435 | Mike Grace | Florida Southern | Chicago (AL) | '04, '05 Outer Banks |
| 15 | 441 | Drew Fiorenza | Clemson | Florida | '05 Wilmington |
| 16 | 485 | Jake Blackwood | Maplewoods (Mo.) CC | Florida | '05 Fayetteville |
| 16 | 491 | Stephen Douglas | East Tennesee State | Cleveland | '06 Wilmington |
| 17 | 506 | Kevin Pucetas | Limestone | San Francisco | '05 Wilson |
| 17 | 508 | John Maschino | Seminole State (Okla.) CC | Texas | '06 Thomasville |
| 17 | 517 | Jayson Miller | Washington State | Philadelphia | '06 New Bern |
| 18 | 550 | J.B. Paxson | Walters State CC | Atlanta | '06 Peninsula |
| 19 | 565 | Todd Davison | Delaware | Baltimore | '03, '04 Outer Banks |
| 19 | 578 | Greg Dowling | Georgia Southern | Oakland | '04 Outer Banks |
| 20 | 589 | Erik Walker | Charlotte | Tampa Bay | '03, '04 Wilson |
| 20 | 596 | Adam Paul | UNC-Wilmington | San Francisco | '04 Wilmington |
| 20 | 604 | Jason Jacobs | Georgia | New York (NL) | '03 Florence |
| 21 | 626 | Steven Calicutt | East Tennessee State | San Francisco | '03 Spartanburg |
| 21 | 637 | Jacob Dempsey | Winthrop | Philadelphia | '03, '04 Outer Banks |
| 21 | 638 | Jake Smith | East Carolina | Oakland | '03 Thomasville |
| 22 | 648 | Jay Cox | North Carolina | Colorado | '04, '05, '06 Fayetteville |
| 22 | 666 | Aaron Tennyson | Kentucky | Minnesota | '03 Petersburg |
| 22 | 671 | Chuck Hargis | East Tennessee State | Cleveland | '05 Fayetteville |
| 23 | 688 | Jay Heafner | Davidson | Texas | '04, '05 Gastonia |
| 23 | 691 | Forrest Beverly | South Carolina | Washington | '05 Florence |
| 23 | 703 | Paul Smyth | San Diego State | Boston | '05 Petersburg |
| 24 | 719 | Matt Matulia | The Citadel | Chicago (NL) | '04, '05 Peninsula |
| 24 | 721 | Ricky Caputo | Hofstra | Washington | '04 Peninsula |
| 24 | 728 | Earl Oakes | Pace | Oakland | '04, '05, '06 Petersburg |
| 25 | 738 | Jeremy Jones | North Carolina A&T | Colorado | '06 Fayetteville |
| 25 | 752 | Mike Goetz | Wisconsin-Milwaukee | Milwaukee | '05 Martinsville |
| 26 | 795 | David Wasylak | Lubbock Christian | Chicago (AL) | '06 Florence |
| 27 | 798 | Matt Repec | Winthrop | Colorado | '03 Wilson |
| 29 | 860 | Brandon Williams | South Carolina Upstate | Pittsburgh | '05 Gastonia |
| 30 | 894 | Lee Tabor | Francis Marion | Cincinnati | '04 Fayetteville / '06 Florence |
| 31 | 931 | Zach Baldwin | West Virginia State | Washington | '04 Wilson |
| 32 | 967 | Alan Robbins | Winthrop | Philadelphia | '03 Spartanburg |
| 32 | 973 | Mike Chambers | Franklin Pierce | Boston | '05 Petersburg |
| 33 | 997 | Mike Deveaux | Georgia Coll. & State Univ. | Philadelphia | '05 Wilmington |
| 34 | 1011 | Stan Posluszny | West Virginia | Florida | '04 Wilmington |
| 34 | 1030 | Matt Morgal | Seminole State (Okla.) CC | Atlanta | '06 Thomasville |
| 36 | 1084 | Edgar Ramirez | Louisiana State | New York (NL) | '04 Edenton / '05 Martinsville |
| 36 | 1095 | Matt Enuco | Rowan | Chicago (AL) | '05 Peninsula |
| 38 | 1132 | Dana Arrowood | Old Dominion | Detroit | '05 Peninsula |
| 38 | 1138 | Jonathan Hollis | Yale | Texas | '05 New Bern |
| 38 | 1152 | Eduardo Chile | Rollins | Los Angeles (AL) | '05 Martinsville |
| 39 | 1179 | Will Kline | Mississippi | Houston | '05 Thomasville |
| 40 | 1195 | David Cash | Florida | Baltimore | '04 Florence |
| 41 | 1232 | Matt Poulk | UNC-Wilmington | Milwaukee | '02, '05 Wilmington |
| 41 | 1237 | Michael Anotnini | Georgia Coll. & State Univ. | Philadelphia | '05, '06 New Bern |
| 44 | 1315 | Justin Brashear | Mississippi | Arizona | '05 Petersburg |
| 44 | 1318 | Kelly Sweppenhiser | Virginia Military Institute | Toronto | '04 Peninsula |
| 45 | 1346 | Elliott Shea | Franklin Pierce | Chicago (NL) | '05 Petersburg |
| 49 | 1456 | Jonathan Batts | UNC-Wilmington | San Francisco | '04 Wilmington / '05 Wilson |